I received my doctor of medicine degree from Creighton University in Omaha, Nebraska and completed my Obstetrics & Gynecology residency at Northwestern University Medical Center in Chicago, Illinois. I then completed my fellowship at The University of Texas MD Anderson Cancer Center in 1993. Prior to joining the M.D. Anderson faculty, I served as Vice Chairman, Department of Obstetrics and Gynecology at the University of Texas, Southwestern Medical Center in Dallas.
My research interests include drug discovery and novel therapeutics for ovarian, uterine, and cervical cancer, clinical trial development and statistical design. I serve as the institution’s Gynecologic Oncology Group (GOG) principal investigator (PI), serve on the NRG’s (formerly the Gynecologic Oncology Group) Ovarian and Developmental Therapeutics Committees, and am PI or co-PI for several GOG prospective clinical trials. I am currently a co-project leader for the MDACC Ovarian SPORE, the MDACC Uterine SPORE, the Ovarian Cancer Research Fund, and the Marcus Foundation, each of which is sponsoring novel therapeutics trials in gynecologic cancers. I also serves as Physician Champion and PI for a new human therapeutic leveraging nanoparticle delivery of gene silencing non-coding RNA (siRNA). I have developed a mentoring program for junior investigator clinical trialists.
I have authored or coauthored over 400 scientific publications, including over 250 peer-reviewed articles, numerous book chapters, monographs, invited articles and textbooks including, The Handbook of Gynecologic Oncology, Clinical Lymphatic Mapping in Gynecologic Cancers, Prognostic and Predictive Factors in Gynecological Cancers, and Atlas of Gynecologic Oncology. In 2012, Iwas elected to the position of Secretary Treasurer for the International Gynecologic Cancer Society, and was Program Chair for their 2012 biannual meeting. In 2015, I was elected President for the Society of Gynecologic Oncology. I currently serve on the Gynecologic Oncology Group’s Board of Directors.